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Thank you for reading our monthly newsletter. This month’s edition is
1,184 words, about a
5-minute read.
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Since 2015, Elysium has been the leader in helping people access, understand, and benefit from scientific breakthroughs in longevity. In the March newsletter, we’re pleased to share several of the ways we’ve been focused on helping people understand longevity science in the past month: a brand new video explaining how NAD+ works in the body, as well as three articles in the news featuring interviews with Elysium scientists, executives, and Scientific Advisory Board members. You’ll also find other media stories that highlight the benefits of
Matter for brain health and
Mosaic for
“visibly healthy, supple and youthful looking skin.”
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What does NAD+ do? This video explains.
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Everyone seems to be talking about NAD+ right now. This essential coenzyme is found in every one of your cells, and it’s involved in hundreds of cellular processes, including the most fundamental: creating ATP, the energy that powers our cells and our bodies. In other words, widespread interest in NAD+ is no passing health fad or wellness trend; it’s built on decades of rigorous longevity science from the world’s top researchers, including Elysium co-founder and chief scientist
Leonard Guarente, Ph.D. If you’re new to NAD+ science or looking to brush up on the benefits of NAD+ supplementation, watch this video for a deep dive in about a minute.
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You’re Built for Longevity
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Everyone deserves to enjoy a healthy life at every age—and it’s within reach. If you’re ready to start a health routine that’s built for longevity, use the code LONGEVITY at checkout for 25% off your first month of Basis. Clinically proven to increase your NAD+ levels by 40% to combat aging at the deepest level—in your cells.
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 chooses Mosaic for skin hydration and healthy aging
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chooses Mosaic for skin hydration and healthy aging
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With winter only days behind us, many of us have at least some experience with dry, dull, cracked, or rough skin.
Forbes contributor Kate Donnelly offers guidance, with the help of
Richard Granstein, M.D., chair of the Department of Dermatology at Weill Cornell Medicine and Elysium Scientific Advisory Board member, on regaining moisture and glow with a list of five skin-hydrating supplements that also support healthy aging. First up on her list is
Mosaic. Donnelly points to Mosaic’s clinically proven Phytonutrient Carotenoid Complex in combination with hyaluronic acid. Together, these ingredients combat stressors and increase moisture levels, driving healthy changes from the inside.
“The result? Visibly healthy, supple and youthful looking skin.”
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 selects Matter as top wellness product for perimenopause and menopause
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People are increasingly talking about the health challenges that come with perimenopause and menopause, according to
Harper’s Bazaar writer Lindy Sigel. Sigel teams up with a board-certified dermatologist to select 19 beauty and wellness products to support the skin, hair, and body through these changes.
Matter stands out as one of the only products that isn’t a cream, mist, shampoo, balm, or peel pad.
“Anyone can benefit from this brain health supplement,” Sigel writes.
“Filled with omega-3s, antioxidants, and a patented tri-vitamin complex, these supplements target shrinking gray matter, which controls the active parts of your brain, like memory and balance.”
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 leans into longevity with Index
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Biological age is the age your body is expected to perform, or as
Town and Country writer Gwen Flamberg puts it,
“an overall measure of what makes you tick—and how efficiently.” And it’s primarily influenced by lifestyle decisions and factors as opposed to genetics. That’s good news if you’re open to modifying your lifestyle.
Flamberg offers several ways to track and optimize your biological age, including taking
Index,
“a nifty DIY saliva-sample test kit can be done in the comfort of your own home yet yields major science-backed results.” As she points out, Index measures 10 different aspects of aging and was developed in partnership with leading epigenetics researcher Morgan Levine, Ph.D., of Yale University. Elysium’s chief scientist
Leonard Guarente, Ph.D., is also interviewed in the article, where he suggests taking an
NAD+ supplement to restore levels of the essential coenzyme lost with age.
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 navigates skin supplements with Elysium experts
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navigates skin supplements with Elysium experts
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The Zoe Report created an in-depth guide to skin supplements—think collagens, hyaluronic acid, vitamin A, and proprietary formulations like
Mosaic—and we were thrilled that they called on Elysium experts to help their readers navigate the market. Beauty writer Megan McIntyre interviewed Elysium’s CEO
Eric Marcotulli and chief product officer
Mark Morris about a variety of topics, including how to understand claims on labels and in advertisements, identifying meaningful clinical research, and what to look for in ingredient formulations. Here are two takeaways from Marcotulli and Morris, and we recommend reading the guide for more great advice.
Marcotulli:
“From our standpoint, rather than asking a company ‘What do your supplements do?’, the better question is ‘Has this formula been tested in people and has that been published under peer review?’”
Morris:
“If you’re seeing proprietary blends with 14 different things in it, that’s pixie dust. You just don’t have the footprint to put things at efficacious doses like that. So it’s really looking at a label that is cleaner, that has a few key ingredients—that you could easily Google because you know that must be what’s powering the product. If the label looks overwhelming, put it back on the shelf.”
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 interviews Leonard Guarente, Ph.D., about diet and exercise mimetics
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interviews Leonard Guarente, Ph.D., about diet and exercise mimetics
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Calorie restriction (CR) and exercise are both longevity-promoting protocols—and researchers are seeking to capture their benefits inside a pill or capsule. CR and exercise “mimetics” are the subject of a recent article in
Medscape featuring Elysium’s chief scientist
Leonard Guarente, Ph.D. The article points to research showing that calorie restriction slows aging and promotes healthspan in model organisms and in humans by shifting metabolic processes to protect against damage and stress. Some of the most promising CR mimetics being studied are the NAD+ precursors
nicotinamide riboside (NR) and
nicotinamide mononucleotide (NMN), which have already shown a variety of benefits in human clinical trials. For example, in a study conducted by Elysium, NR supplementation reduced markers of inflammation in the liver.
"I think it was a pretty interesting result," Dr. Guarente says in the article.
"Fatty liver progressively damages the liver. This has the potential to slow that down." Read the full story for more details about the NAD+ studies as well as exercise mimetics.
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QUOTE OF THE MONTH
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“Aging well means to me being able to do whatever I want to do when I want to do it. So, I’ve been taking
Basis for years.”
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–Pamela Olin, Basis user since 2016
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Share your healthy
aging breakthroughs
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We’d love to hear from you! If you have a story to share about your experience with Elysium products, we want to celebrate your health journey. Please email
care@elysiumhealth.com and your story may be featured in an upcoming newsletter or on our social media channels.
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